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Latest workflows used for determining the MOA of novel compounds normally include an assortment of useful screening assays incorporating a myriad of isolated biological targets. These methods typically usually do not file purpose in the dynamic natural environment where these targets normally reside. This is especially critical for ion channel targ
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The original Cochrane evaluation on this topic (Yelland 2004B) was executed to focus only on prolotherapy injections, subsequent an earlier Cochrane assessment of all injection therapies for low‐back pain (Nelemans 2003) in which the sole treatment method that confirmed sizeable, sustained reductions in pain and disability at 6 months included pr